Shanghai Jinma explains the conditions of animal serum to ensure quality assurance? -Huaqiang Electronic Network

In cell culture experiments, serum is often used as an additive to the underlying growth medium. Whether or not to add serum during the experiment depends mainly on the chemical composition of the basic medium, the type of cultured cells, and the culture system. The quality of serum greatly affects the experimental results. Many customers ask questions when purchasing: What conditions do animal serums guarantee? Shanghai Jinma gives you a comment:
First, the collection of serum in the production process, the whole blood is collected using a sterile disposable plastic bag, to be separated after coagulation, and the serum is collected and stored frozen. Controlling initial collection is a key factor in controlling the quality of the final serum product. Production is allowed only if the starting materials meet our specifications.
Second, the choice of raw materials for the product There are two fetal bovine serum standards in the global market: the US Department of Agriculture Standard (USDA) and European standards. The US Department of Agriculture standard, the original serum must be taken from countries where there is no mad cow disease (BSE) and foot-and-mouth disease (FMD) epidemic, before it can be freely imported into any country for safe production. Moreover, researchers only use serum that meets this standard before they are allowed to send their cells and cell products to other countries that also have strict import terms for cooperation and exchange. All Shanghai Hengyuan Biological Company fetal bovine serum meets USDA standards.
Third, the treatment process strictly requires several batches of frozen serum to be thawed, and the endotoxin and heme content are checked, and the standard can be thoroughly mixed under refrigeration to continue processing, and further filtered and sterilized. Shanghai Hengyuan Biotech Co., Ltd. successively treated fetal bovine serum by pre-filtration and membrane filtration. The final filtration step was three consecutive filtrations with a 100 nm filter. At the end of the filtration, the serum is dispensed in an aseptic process, and the entire process is effective to ensure the final product is sterile. The air cleanliness of serum production is 100. All dispensing stations are filtered through a high-efficiency particulate air filter and maintained in a positive pressure dispensing environment to monitor total particulates, suspended particulates and pressure. After dispensing, the final product is quickly frozen at -20 degrees and isolated until all quality control tests are completed.
Fourth, FBS quality control Each batch of serum products is confirmed to meet the various standards and is recorded in the quality inspection report in writing.
Fifth, the serum quality is 100% to ensure that the production process is carried out under a strictly controlled condition. UV sterilization, filtration sterilization and dispensing are key production steps that ensure serum quality. The data related to serum production is recorded as a special archive, from the initial collection of raw materials to the entire production process of finished product storage, as well as quality control tests and results are documented, and the source files can be traced under monitoring conditions. Shanghai Hengyuan Bio-Products Co., Ltd. meets quality management standards ISO9001:2000 and ISO 13485:2003, and can provide supporting documents.
I hope that these provided by Shanghai Jinma can effectively help you solve problems. If you have any questions, please come to e-consultation.