A new study from Yale University and others pointed out that mutations in a gene that controls lipid metabolism may trigger a slow-progressive neurogenic disease characterized by myelin, a related study or to reveal multiple control The new treatment for sexual sclerosis provides ideas, and the study was published in the international journal Nature Cell Biology .
In the article, the researchers point out that a single gene mutation called FAM126A triggers a series of pathological lesions, such as developmental delay, mental retardation, peripheral neuropathy, and muscle atrophy. It also causes congenital cataracts, but Researchers are not aware of the precise function of the gene.
Researcher Pietro De Camilli said that we found that the protein hyccin encoded by the FAM126A gene can help produce a lipid that is important for myelination, which surrounds and protects axons in neuronal cells throughout the nervous system; In this study, researchers combined with researchers from the United States, Italy, and other countries to analyze cells in patients with myelin degeneration and congenital cataract found that mutations in the gene FAM126A lead to enzyme complexes that are important for myelin production. Loss of stability.
In patients with multiple sclerosis, the progression of the disease mainly depends on the re-generation of myelin, and the immune system of the patient's body often attacks the myelin sheath, eventually leading to neuronal death; the researchers speculate that the body is developing normally. Hyccin plays a crucial role in the production of myelin in the recovery phase of patients with multiple sclerosis; in the later studies, researchers may conduct extensive research on a large number of samples to develop neurological diseases such as multiple sclerosis. The new therapies provide a basis for research.
Laptop power adapter charger for Dell:
Laptop Model | Adapter Output |
Latitude E5400 E5410 E5500 E5510 | 19.5v 4.62a, 7450 |
Studio XPS 16 (1645)1640 1645 1647 | 19.5v 4.62a, 7450 |
Studio XPS M1645 M1647 | 19.5v 4.62a, 7450 |
XPS 14 15 17 L501x L502x L702x L702x | 19.5v 4.62a, 7450 |
Inspiron 1464 1564 1764 | 19.5v 4.62a, 7450 |
Inspiron 1525 1440 1526 | 19.5v 3.34a, 7450 |
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Inspiron N5050 N4010 N5110 | 19.5v 3.34a, 7450 |
Inspiron 14Z-N411Z 13Z N311Z | 19.5v 4.62a, 7450 |
Inspiron 1545 | 19.5v 3.34a, 7450 |
Latitude E5420 E5530 E5430 E6420 | 19.5v 4.62a, 7450 |
Inspiron 1440 1525 1526 1545 1750 | 19.5v 3.34a, Octagon tip |
Inspiron 1300 B120 B130 | 19v 3.16a/3.42, 5525 |
Inspiron 1525 1526 1545 | 19.5v 3.34a, 7450 |
Studio 1440 1440n 1440z 14z 14zn | 19.5v 3.34a, 7450 |
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Inspiron 13Z 13ZD 13ZR M301 M301z M301ZD M301ZR N301 | 19.5v 3.34a, 7450 |
Inspiron N301Z N301ZD N301ZR | 19.5v 3.34a, 7450 |
Studio 1535 1536 1555 1557 1558 | 19.5v 4.62a, 7450 |
Latitude E5420 E5520 E6430 E6530 E6420 E6520 | 19.5v 4.62a, 7450 |
Inspiron Mini 10 10v 1010 1010n 1010v 1011 1011n 1011v | 19v 1.58a, 5517 |
Inspiron 14V 14VR M4010 N4020 N4030 | 19.5v 4.62a, 7450 |
Inspiron N4110 N5110 N7110 M5010 | 19.5v 3.34a, 7450 |
630M 640M E1405 | 19.5v 4.62a, 7450 |
Inspiron 15-3521 17-3721 | 19.5v 3.34a, 7450 |
Latitude 120L | 19.5v 3.34a, 7450 |
Vostro 1710 1710n 1720 1720n | 19.5v 4.62a, 7450 |
Vostro 1500 1700 Inspiron 1520 1521 1720 | 19.5v 4.62a, 7450 |
Vostro 1400 1420 PP26L | 19.5v 3.34a, 7450 |
Latitude D410 | 19.5v 3.34a, 7450 |
Inspiron 1120, 1121, M101 | 19.5v 3.34a, 7450 |
Inspiron Mini 1012 1018 | 19v 1.58a, 5517 |
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